SYNJ2 Antibody

ProSci
Product Code: PSI-60-807
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-807-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Further Information

Additional Names:
Synaptojanin-2, Synaptic inositol 1,5-trisphosphate 5-phosphatase 2, SYNJ2, KIAA0348
Application Note:
For WB starting dilution is: 1:1000
Background:
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.
Background References:
  • Rikova, K., et al. Cell 131(6):1190-1203(2007)
  • Ieguchi, K., et al. J. Biol. Chem. 282(32):23296-23305(2007)
  • Rossi, M.R., et al. Cancer Genet. Cytogenet. 161(2):97-103(2005)
  • Chuang, Y.Y., et al. Cancer Res. 64(22):8271-8275(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SYNJ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 679-707 amino acids from the Central region of human SYNJ2.
NCBI Gene ID #:
8871
NCBI Official Name:
Synaptojanin-2
NCBI Official Symbol:
SYNJ2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
166 kDa
Protein Accession #:
O15056
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O15056
User NOte:
Optimal dilutions for each application to be determined by the researcher.