COL4A6 Antibody
| Code | Size | Price |
|---|
| PSI-59-095-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Collagen alpha-6(IV) chain, COL4A6
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes one of the six subunits of type IV
collagen, the major structural component of basement membranes.
Like the other members of the type IV collagen gene family, this
gene is organized in a head-to-head conformation with another type
IV collagen gene, alpha 5 type IV collagen, so that the gene pair
shares a common promoter. Deletions in the alpha 5 gene that extend
into the alpha 6 gene result in diffuse leiomyomatosis accompanying
the X-linked Alport syndrome caused by the deletion in the alpha 5
gene. Two splice variants have been identified for this gene.
Background References:
- Romero, R., et al. Am. J. Obstet. Gynecol. (2010) In press :
- Bailey, S.D., et al. Diabetes Care (2010) In press :
- Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This COL4A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 830-859 amino acids from the Central region of human COL4A6.
NCBI Gene ID #:
1288
NCBI Official Name:
Collagen alpha-6(IV) chain
NCBI Official Symbol:
COL4A6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
164 kDa
Protein Accession #:
Q14031
Protein GI Number:
116241307
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q14031
User NOte:
Optimal dilutions for each application to be determined by the researcher.