SNX13 Antibody
| Code | Size | Price |
|---|
| PSI-56-298-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Sorting nexin-13, RGS domain- and PHOX domain-containing protein, RGS-PX1, SNX13, KIAA0713
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a PHOX domain- and RGS domain-containing
protein that belongs to the sorting nexin (SNX) family and the
regulator of G protein signaling (RGS) family. The PHOX domain is a
phosphoinositide binding domain, and the SNX family members are
involved in intracellular trafficking. The RGS family members are
regulatory molecules that act as GTPase activating proteins for G
alpha subunits of heterotrimeric G proteins. The RGS domain of this
protein interacts with G alpha(s), accelerates its GTP hydrolysis,
and attenuates G alpha(s)-mediated signaling. Overexpression of
this protein delayes lysosomal degradation of the epidermal growth
factor receptor. Because of its bifunctional role, this protein may
link heterotrimeric G protein signaling and vesicular trafficking.
Background References:
- Rose, J. Phd, et al. Mol. Med. (2010) In press :
- Hillman, R.T., et al. Genome Biol.(2), R8 (2004) :
- Worby, C.A., et al. Nat. Rev. Mol. Cell Biol. 3(12):919-931(2002)
- Kosan, C., et al. Cytogenet. Genome Res. 97 (3-4), 167-170 (2002) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This SNX13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-807 amino acids from the C-terminal region of human SNX13.
NCBI Gene ID #:
23161
NCBI Official Name:
Sorting nexin-13
NCBI Official Symbol:
SNX13
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
112 kDa
Protein Accession #:
Q9Y5W8
Protein GI Number:
24418867
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9Y5W8
User NOte:
Optimal dilutions for each application to be determined by the researcher.