TRPC7 Antibody

ProSci
Product Code: PSI-58-768
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-768-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in CEM cell line lysates (35ug/lane).

Western blot analysis in CEM cell line lysates (35ug/lane).

Further Information

Additional Names:
Short transient receptor potential channel 7, TrpC7, Transient receptor protein 7, TRP-7, hTRP7, TRPC7, TRP7
Application Note:
For WB starting dilution is: 1:1000
Background:
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.
Background References:
  • Rose, J. Phd, et al. Mol. Med. (2010) In press :
  • Miyagi, K., et al. J. Biol. Chem. 284(49):34400-34412(2009)
  • Graubert, T.A., et al. PLoS ONE(2), E4583 (2009) :
  • Abed, E., et al. Cell Prolif. 40(6):849-865(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TRPC7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 834-862 amino acids from the C-terminal region of human TRPC7.
NCBI Gene ID #:
57113
NCBI Official Name:
Short transient receptor potential channel 7
NCBI Official Symbol:
TRPC7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
100 kDa
Protein Accession #:
Q9HCX4
Protein GI Number:
18202960
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9HCX4
User NOte:
Optimal dilutions for each application to be determined by the researcher.