GBP4 Antibody

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ProSci
Product Code: PSI-59-560
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-560-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

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Western blot analysis in HepG2 cell line lysates (35ug/lane).
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Western blot analysis in HepG2 cell line lysates (35ug/lane).

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Further Information

Additional Names:
Guanylate-binding protein 4, GTP-binding protein 4, GBP-4, Guanine nucleotide-binding protein 4, GBP4
Application Note:
For WB starting dilution is: 1:1000
Background:
Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
  • Olszewski, M.A., et al. J. Interferon Cytokine Res. 26(5):328-352(2006)
  • Vestal, D.J. J. Interferon Cytokine Res. 25(8):435-443(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GBP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 370-396 amino acids from the Central region of human GBP4.
NCBI Gene ID #:
115361
NCBI Official Name:
Guanylate-binding protein 4
NCBI Official Symbol:
GBP4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
73 kDa
Protein Accession #:
Q96PP9
Protein GI Number:
116242487
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q96PP9
User NOte:
Optimal dilutions for each application to be determined by the researcher.