ARHGAP22 Antibody

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ProSci
Product Code: PSI-56-795
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-795-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution Lane 1: K562 whole cell lysate Lane 2: U-87 MG whole cell lysate Lysates/proteins at 20 ug per lane.
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Western blot analysis in MDA-MB231,WiDr,ZR-75-1 cell line lysates (35ug/lane).
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Western Blot at 1:1000 dilution Lane 1: K562 whole cell lysate Lane 2: U-87 MG whole cell lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in MDA-MB231,WiDr,ZR-75-1 cell line lysates (35ug/lane).

Documents

Further Information

Additional Names:
Rho GTPase-activating protein 22, Rho-type GTPase-activating protein 22, ARHGAP22, RHOGAP2
Application Note:
For WB starting dilution is: 1:1000
Background:
ARHGAPs, such as ARHGAP22, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Dick, D.M., et al. Mol. Psychiatry (2010) In press :
  • Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
  • Katoh, M., et al. Int. J. Mol. Med. 14(2):333-338(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ARHGAP22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-633 amino acids from the C-terminal region of human ARHGAP22.
NCBI Gene ID #:
58504
NCBI Official Name:
Rho GTPase-activating protein 22
NCBI Official Symbol:
ARHGAP22
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
77 kDa
Protein Accession #:
Q7Z5H3
Protein GI Number:
74750129
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q7Z5H3
User NOte:
Optimal dilutions for each application to be determined by the researcher.