OSBPL1A Antibody

ProSci
Product Code: PSI-58-741
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-741-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Hela cell line lysates (35ug/lane).

Western blot analysis in Hela cell line lysates (35ug/lane).

Further Information

Additional Names:
Oxysterol-binding protein-related protein 1, ORP-1, OSBP-related protein 1, OSBPL1A, ORP1, OSBP8, OSBPL1, OSBPL1B
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Hsu, Y.H., et al. PLoS Genet.(6), E1000977 (2010) :
  • Rocha, N., et al. J. Cell Biol. 185(7):1209-1225(2009)
  • Melzer, D., et al. PLoS Genet.(5), E1000072 (2008) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This OSBPL1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 736-763 amino acids from the C-terminal region of human OSBPL1A.
NCBI Gene ID #:
114876
NCBI Official Name:
Oxysterol-binding protein-related protein 1
NCBI Official Symbol:
OSBPL1A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
108 kDa
Protein Accession #:
Q9BXW6
Protein GI Number:
20143880
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9BXW6
User NOte:
Optimal dilutions for each application to be determined by the researcher.