DSC3 Antibody
| Code | Size | Price |
|---|
| PSI-58-711-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Desmocollin-3, Cadherin family member 3, Desmocollin-4, HT-CP, DSC3, CDHF3, DSC4
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a calcium-dependent
glycoprotein that is a member of the desmocollin subfamily of the
cadherin superfamily. These desmosomal family members, along with
the desmogleins, are found primarily in epithelial cells where they
constitute the adhesive proteins of the desmosome cell-cell
junction and are required for cell adhesion and desmosome
formation. The desmosomal family members are arranged in two
clusters on chromosome 18, occupying less than 650 kb combined.
Alternative splicing results in two transcript variants encoding
distinct isoforms.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
- Spindler, V., et al. J. Biol. Chem. 284(44):30556-30564(2009)
- Ayub, M., et al. Am. J. Hum. Genet. 85(4):515-520(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DSC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 822-850 amino acids from the C-terminal region of human DSC3.
NCBI Gene ID #:
1825
NCBI Official Name:
Desmocollin-3
NCBI Official Symbol:
DSC3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
100 kDa
Protein Accession #:
Q14574
Protein GI Number:
116241342
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q14574
User NOte:
Optimal dilutions for each application to be determined by the researcher.