TBCA Antibody
Code | Size | Price |
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PSI-56-791-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Tubulin-specific chaperone A, TCP1-chaperonin cofactor A, Tubulin-folding cofactor A, CFA, TBCA
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of this gene is one of four proteins
(cofactors A, D, E, and C) involved in the pathway leading to
correctly folded beta-tubulin from folding intermediates. Cofactors
A and D are believed to play a role in capturing and stabilizing
beta-tubulin intermediates in a quasi-native confirmation. Cofactor
E binds to the cofactor D/beta-tubulin complex; interaction with
cofactor C then causes the release of beta-tubulin polypeptides
that are committed to the native state. This gene encodes
chaperonin cofactor A.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
- Bruneel, A., et al. Proteomics 5(15):3876-3884(2005)
- Nolasco, S., et al. FEBS Lett. 579(17):3515-3524(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rb
Immunogen:
This TBCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human TBCA.
NCBI Gene ID #:
6902
NCBI Official Name:
Tubulin-specific chaperone A
NCBI Official Symbol:
TBCA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
13 kDa
Protein Accession #:
O75347
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O75347
User NOte:
Optimal dilutions for each application to be determined by the researcher.