NDST4 Antibody
| Code | Size | Price |
|---|
| PSI-59-647-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4, Glucosaminyl N-deacetylase/N-sulfotransferase 4, NDST-4, N-heparan sulfate sulfotransferase 4, N-HSST 4, Heparan sulfate N-deacetylase 4, 3---, Heparan sulfate N-sulfotransferase 4, 282-, NDST4, HSST4
Application Note:
For WB starting dilution is: 1:1000
Background:
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity (By similarity).
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
- Treutlein, J., et al. Arch. Gen. Psychiatry 66(7):773-784(2009)
- Aikawa, J., et al. J. Biol. Chem. 276(8):5876-5882(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NDST4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-212 amino acids from the N-terminal region of human NDST4.
NCBI Gene ID #:
64579
NCBI Official Name:
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4
NCBI Official Symbol:
NDST4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
101 kDa
Protein Accession #:
Q9H3R1
Protein GI Number:
74718249
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9H3R1
User NOte:
Optimal dilutions for each application to be determined by the researcher.