DNALI1 Antibody

ProSci
Product Code: PSI-58-607
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-607-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in T47D cell line lysates (35ug/lane).

Western blot analysis in T47D cell line lysates (35ug/lane).

Further Information

Additional Names:
Axonemal dynein light intermediate polypeptide 1, Inner dynein arm light chain, axonemal, hp28, DNALI1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Combs, J., et al. Proc. Natl. Acad. Sci. U.S.A. 103(40):14883-14888(2006)
  • Kastury, K., et al. J. Clin. Endocrinol. Metab. 82(9):3047-3053(1997)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat
Immunogen:
This DNALI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-243 amino acids from the C-terminal region of human DNALI1.
NCBI Gene ID #:
7802
NCBI Official Name:
Axonemal dynein light intermediate polypeptide 1
NCBI Official Symbol:
DNALI1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
O14645
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O14645
User NOte:
Optimal dilutions for each application to be determined by the researcher.