RREB1 Antibody

ProSci
Product Code: PSI-60-287
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-60-287-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Further Information

Additional Names:
Ras-responsive element-binding protein 1, RREB-1, Finger protein in nuclear bodies, Raf-responsive zinc finger protein LZ321, Zinc finger motif enhancer-binding protein 1, Zep-1, RREB1, FINB
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Neale, B.M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(16):7395-7400(2010)
  • Milon, B.C., et al. Prostate 70(3):288-296(2010)
  • Flajollet, S., et al. J. Immunol. 183(11):6948-6959(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RREB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1398-1424 amino acids from the C-terminal region of human RREB1.
NCBI Gene ID #:
6239
NCBI Official Name:
Ras-responsive element-binding protein 1
NCBI Official Symbol:
RREB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
181 kDa
Protein Accession #:
Q92766
Protein GI Number:
152031673
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q92766
User NOte:
Optimal dilutions for each application to be determined by the researcher.