PPFIBP1 Antibody
| Code | Size | Price |
|---|
| PSI-59-212-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Liprin-beta-1, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1, PTPRF-interacting protein-binding protein 1, hSGT2, PPFIBP1, KIAA1230
Application Note:
For WB starting dilution is: 1:2000
Background:
The protein encoded by this gene is a member of the LAR
protein-tyrosine phosphatase-interacting protein (liprin) family.
Liprins interact with members of LAR family of transmembrane
protein tyrosine phosphatases, which are known to be important for
axon guidance and mammary gland development. It has been proposed
that liprins are multivalent proteins that form complex structures
and act as scaffolds for the recruitment and anchoring of LAR
family of tyrosine phosphatases. This protein was found to interact
with S100A4, a calcium-binding protein related to tumor
invasiveness and metastasis. In vitro experiment demonstrated that
the interaction inhibited the phosphorylation of this protein by
protein kinase C and protein kinase CK2. Alternatively spliced
transcript variants encoding distinct isoforms have been reported.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Norrmen, C., et al. Blood 115(4):906-909(2010)
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PPFIBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-617 amino acids from the Central region of human PPFIBP1.
NCBI Gene ID #:
8496
NCBI Official Name:
Liprin-beta-1
NCBI Official Symbol:
PPFIBP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
114 kDa
Protein Accession #:
Q86W92
Protein GI Number:
90185247
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q86W92
User NOte:
Optimal dilutions for each application to be determined by the researcher.