MNK2 Antibody

ProSci
Product Code: PSI-62-689
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-62-689-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution + Hela whole cell lysate Lysates/proteins at 20 ug per lane.
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Western blot analysis of MNK2 (MKNK2) antibody in 293 cell line lysates (35ug/lane)

Western Blot at 1:1000 dilution + Hela whole cell lysate Lysates/proteins at 20 ug per lane.
Western blot analysis of MNK2 (MKNK2) antibody in 293 cell line lysates (35ug/lane)

Further Information

Additional Names:
MAP kinase-interacting serine/threonine-protein kinase 2, MAP kinase signal-integrating kinase 2, MAPK signal-integrating kinase 2, Mnk2, MKNK2, GPRK7, MNK2
Application Note:
For WB starting dilution is: 1:1000
Background:
MKNK2 may play a role in the response to environmental stress and cytokines. This protein appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
Background References:
  • Scheper, G.C., et al., Mol. Cell. Biol. 23(16):5692-5705 (2003). Knauf, U., et al., Mol. Cell. Biol. 21(16):5500-5511 (2001). Scheper, G.C., et al., Mol. Cell. Biol. 21(3):743-754 (2001). Slentz-Kesler, K., et al., Genomics 69(1):63-71 (2000). Haribabu, B., et al., Proc. Natl. Acad. Sci. U.S.A. 90(20):9398-9402 (1993).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MNK2 (MKNK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-432 amino acids from the C-terminal region of human MNK2 (MKNK2).
NCBI Gene ID #:
2872
NCBI Official Name:
MAP kinase-interacting serine/threonine-protein kinase 2
NCBI Official Symbol:
MKNK2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
Q9HBH9
Protein GI Number:
90102033
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q9HBH9
User NOte:
Optimal dilutions for each application to be determined by the researcher.