PAFAH2 Antibody
| Code | Size | Price |
|---|
| PSI-59-174-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Platelet-activating factor acetylhydrolase 2, cytoplasmic, Serine-dependent phospholipase A2, SD-PLA2, hSD-PLA2, PAFAH2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes platelet-activating factor
acetylhydrolase isoform 2, a single-subunit intracellular enzyme
that catalyzes the removal of the acetyl group at the SN-2 position
of platelet-activating factor (identified as
1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this
lipase exhibits a broader substrate specificity than simply
platelet activating factor. Two other isoforms of intracellular
platelet-activating factor acetylhydrolase exist, and both are
multi-subunit enzymes. Additionally, there is a single-subunit
serum isoform of this enzyme.
Background References:
- Schmidt, E.B., et al. Atherosclerosis 196(1):420-424(2008)
- Umemura, K., et al. Stroke 38(3):1063-1068(2007)
- Unno, N., et al. J. Surg. Res. 134(1):36-43(2006)
- Marques, M., et al. J. Invest. Dermatol. 119(4):913-919(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PAFAH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-276 amino acids from the Central region of human PAFAH2.
NCBI Gene ID #:
5051
NCBI Official Name:
Platelet-activating factor acetylhydrolase 2, cytoplasmic
NCBI Official Symbol:
PAFAH2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q99487
Protein GI Number:
6647691
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q99487
User NOte:
Optimal dilutions for each application to be determined by the researcher.