BLOC1S3 Antibody
| Code | Size | Price |
|---|
| PSI-60-771-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Biogenesis of lysosome-related organelles complex 1 subunit 3, BLOC-1 subunit 3, BLOC1S3, BLOS3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that is a component of the
BLOC1 multi-subunit protein complex. This complex is necessary for
the biogenesis of specialized organelles of the endosomal-lysosomal
system, including platelet dense granules and melanosomes.
Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease
characterized by lysosomal storage defects, bleeding due to
platelet storage pool deficiency, and oculocutaneous albinism.
Background References:
- Seshadri, S., et al. JAMA 303(18):1832-1840(2010)
- Lowe, J.K., et al. PLoS Genet.(2), E1000365 (2009) :
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Morgan, N.V., et al. Am. J. Hum. Genet. 78(1):160-166(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This BLOC1S3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-202 amino acids from the C-terminal region of human BLOC1S3.
NCBI Gene ID #:
388552
NCBI Official Name:
Biogenesis of lysosome-related organelles complex 1 subunit 3
NCBI Official Symbol:
BLOC1S3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
Q6QNY0
Protein GI Number:
74749299
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q6QNY0
User NOte:
Optimal dilutions for each application to be determined by the researcher.