PFN2 Antibody

ProSci
Product Code: PSI-58-192
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-192-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Y79 cell line lysates (35ug/lane).

Western blot analysis in Y79 cell line lysates (35ug/lane).

Further Information

Additional Names:
Profilin-2, Profilin II, PFN2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.
Background References:
  • Shao, J., et al. Mol. Cell. Biol. 28(17):5196-5208(2008)
  • Rikova, K., et al. Cell 131(6):1190-1203(2007)
  • Xu, J., et al. Cell. Signal. 19(7):1575-1582(2007)
  • Stelzl, U., et al. Cell 122(6):957-968(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Rat
Immunogen:
This PFN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-139 amino acids from the C-terminal region of human PFN2.
NCBI Gene ID #:
5217
NCBI Official Name:
Profilin-2
NCBI Official Symbol:
PFN2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
15 kDa
Protein Accession #:
P35080
Protein GI Number:
20178322
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P35080
User NOte:
Optimal dilutions for each application to be determined by the researcher.