TP53RK Antibody

ProSci
Product Code: PSI-58-875
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-875-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution Lane 1: Jurkat whole cell lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 ug per lane.
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Western blot analysis in HL-60 cell line lysates (35ug/lane).

Western Blot at 1:1000 dilution Lane 1: Jurkat whole cell lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in HL-60 cell line lysates (35ug/lane).

Further Information

Additional Names:
TP53-regulating kinase, Atypical serine/threonine protein kinase TP53RK, EKC/KEOPS complex subunit TP53RK, 36--, Nori-2, p53-related protein kinase, TP53RK, C20orf64, PRPK
Application Note:
For WB starting dilution is: 1:1000
Background:
Protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation.
Background References:
  • Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
  • Facchin, S., et al. Cell. Mol. Life Sci. 64 (19-20), 2680-2689 (2007) :
  • Abe, Y., et al. Biochem. Biophys. Res. Commun. 344(1):377-385(2006)
  • Facchin, S., et al. FEBS Lett. 549 (1-3), 63-66 (2003) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This TP53RK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-250 amino acids from the C-terminal region of human TP53RK.
NCBI Gene ID #:
112858
NCBI Official Name:
TP53-regulating kinase
NCBI Official Symbol:
TP53RK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
Q96S44
Protein GI Number:
26398348
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q96S44
User NOte:
Optimal dilutions for each application to be determined by the researcher.