PRKRIR Antibody
| Code | Size | Price |
|---|
| PSI-58-044-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
52 kDa repressor of the inhibitor of the protein kinase, p52rIPK, 58 kDa interferon-induced protein kinase-interacting protein, p58IPK-interacting protein, Death-associated protein 4, THAP domain-containing protein 0, PRKRIR, DAP4, P52RIPK, THAP0
Application Note:
For WB starting dilution is: 1:1000
Background:
Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth.
Background References:
- Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
- Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
- Lee, J.H., et al. KoreanGastroenterol 42(6):484-495(2003)
- Lin, Y., et al. J. Biol. Chem. 277(50):47991-48001(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PRKRIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the N-terminal region of human PRKRIR.
NCBI Gene ID #:
5612
NCBI Official Name:
52 kDa repressor of the inhibitor of the protein kinase
NCBI Official Symbol:
PRKRIR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
O43422
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O43422
User NOte:
Optimal dilutions for each application to be determined by the researcher.