SSH1 Antibody
| Code | Size | Price |
|---|
| PSI-60-530-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein phosphatase Slingshot homolog 1, SSH-like protein 1, SSH-1L, hSSH-1L, SSH1, KIAA1298, SSH1L
Application Note:
For WB starting dilution is: 1:1000
Background:
The ADF (actin-depolymerizing factor)/cofilin family (see
MIM 601442) is composed of stimulus-responsive mediators of actin
dynamics. ADF/cofilin proteins are inactivated by kinases such as
LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to
play a role in actin dynamics by reactivating ADF/cofilin proteins
in vivo (Niwa et al., 2002 [PubMed 11832213]).
Background References:
- Song, S.Y., et al. APMIS 118(5):389-393(2010)
- Peterburs, P., et al. Cancer Res. 69(14):5634-5638(2009)
- Kligys, K., et al. Biochem. Biophys. Res. Commun. 383(4):450-454(2009)
- Kim, J.S., et al. Mol. Biol. Cell 20(11):2650-2660(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This SSH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human SSH1.
NCBI Gene ID #:
54434
NCBI Official Name:
Protein phosphatase Slingshot homolog 1
NCBI Official Symbol:
SSH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
116 kDa
Protein Accession #:
Q8WYL5
Protein GI Number:
82582267
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8WYL5
User NOte:
Optimal dilutions for each application to be determined by the researcher.