KRT75 Antibody
| Code | Size | Price |
|---|
| PSI-58-736-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Keratin, type II cytoskeletal 75, Cytokeratin-75, CK-75, Keratin-6 hair follicle, hK6hf, Keratin-75, K75, Type II keratin-K6hf, Type-II keratin Kb18, KRT75, K6HF, KB18
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the type II keratin family
clustered on the long arm of chromosome 12. Type I and type II
keratins heteropolymerize to form intermediate-sized filaments in
the cytoplasm of epithelial cells. This gene is expressed in the
companion layer, upper germinative matrix region of the hair
follicle, and medulla of the hair shaft. The encoded protein plays
an essential role in hair and nail formation. Variations in this
gene have been associated with the hair disorders
pseudofolliculitis barbae (PFB) and loose anagen hair syndrome
(LAHS).
Background References:
- Sperling, L.C., et al. J. Cutan. Pathol. 37(2):243-248(2010)
- Liu, Z.B., et al. Tumori 95(1):53-62(2009)
- Nofech-Mozes, S., et al. Int. J. Surg. Pathol. 16(4):399-406(2008)
- Schweizer, J., et al. J. Cell Biol. 174(2):169-174(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KRT75 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-92 amino acids from the N-terminal region of human KRT75.
NCBI Gene ID #:
9119
NCBI Official Name:
Keratin, type II cytoskeletal 75
NCBI Official Symbol:
KRT75
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
O95678
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O95678
User NOte:
Optimal dilutions for each application to be determined by the researcher.