GUCA1C Antibody
| Code | Size | Price |
|---|
| PSI-60-944-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Guanylyl cyclase-activating protein 3, GCAP 3, Guanylate cyclase activator 1C, GUCA1C, GCAP3
Application Note:
For WB starting dilution is: 1:1000
Background:
GUCA1C stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.
Background References:
- Stephen, R., et al. J. Mol. Biol. 359(2):266-275(2006)
- Imanishi, Y., et al. Eur. J. Neurosci. 15(1):63-78(2002)
- Haeseleer, F., et al. J. Biol. Chem. 274(10):6526-6535(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GUCA1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human GUCA1C.
NCBI Gene ID #:
9626
NCBI Official Name:
Guanylyl cyclase-activating protein 3
NCBI Official Symbol:
GUCA1C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
O95843
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O95843
User NOte:
Optimal dilutions for each application to be determined by the researcher.