PR48 Antibody
| Code | Size | Price |
|---|
| PSI-63-195-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta, PP2A subunit B isoform PR48, Protein phosphatase 2A 48 kDa regulatory subunit, PPP2R3B, PPP2R3L
Application Note:
For WB starting dilution is: 1:1000
Background:
Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. This protein belongs to the B'' family. The B'' family has been further divided into subfamilies. This protein belongs to the beta subfamily of regulatory subunit B''.
Background References:
- Stevens,I., Eur. J. Biochem. 270 (2), 376-387 (2003)
- Yokoyama,N., Oncogene 20 (42), 6057-6065 (2001)
- Yan,Z., Mol. Cell. Biol. 20 (3), 1021-1029 (2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PR48 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human PR48.
NCBI Gene ID #:
102725016, 28227
NCBI Official Name:
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta
NCBI Official Symbol:
PPP2R3B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
Q9Y5P8
Protein GI Number:
158523346
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q9Y5P8
User NOte:
Optimal dilutions for each application to be determined by the researcher.