NUP54 Antibody

ProSci
Product Code: PSI-60-413
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-413-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of anti-NUP54 Pab in mouse heart tissue lysate.

Western blot analysis of anti-NUP54 Pab in mouse heart tissue lysate.

Further Information

Additional Names:
Nucleoporin p54, 54 kDa nucleoporin, NUP54
Application Note:
For WB starting dilution is: 1:1000
Background:
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. NUP54 is a member of the phe-gly (FG) repeat-containing nucleoporin subset.
Background References:
  • Stoffler, D., et al., Curr. Opin. Cell Biol. 11(3):391-401 (1999).
  • Bodoor, K., et al., Biochem. Cell Biol. 77(4):321-329 (1999).
  • Popov, S., et al., J. Biol. Chem. 273(21):13347-13352 (1998).
  • Hu, T., et al., J. Cell Biol. 134(3):589-601 (1996).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NUP54 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-243 amino acids from the Central region of human NUP54.
NCBI Gene ID #:
53371
NCBI Official Name:
Nucleoporin p54
NCBI Official Symbol:
NUP54
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
Q7Z3B4
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Signal Transduction
Swissprot #:
Q7Z3B4
User NOte:
Optimal dilutions for each application to be determined by the researcher.