ARHGAP1 Antibody

ProSci
Product Code: PSI-60-156
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-156-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in A2058 cell line lysates (35ug/lane).

Western blot analysis in A2058 cell line lysates (35ug/lane).

Further Information

Additional Names:
Rho GTPase-activating protein 1, CDC42 GTPase-activating protein, GTPase-activating protein rhoOGAP, Rho-related small GTPase protein activator, Rho-type GTPase-activating protein 1, p50-RhoGAP, ARHGAP1, CDC42GAP, RHOGAP1
Application Note:
For WB starting dilution is: 1:1000
Background:
GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.
Background References:
  • Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)
  • Rivadeneira, F., et al. Nat. Genet. 41(11):1199-1206(2009)
  • Mori, K., et al. J. Biol. Chem. 284(8):5067-5076(2009)
  • Scholz, R.P., et al. J. Cell. Sci. 122 (PT 1), 92-102 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ARHGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the Central region of human ARHGAP1.
NCBI Gene ID #:
392
NCBI Official Name:
Rho GTPase-activating protein 1
NCBI Official Symbol:
ARHGAP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
Q07960
Protein GI Number:
3024550
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q07960
User NOte:
Optimal dilutions for each application to be determined by the researcher.