KIF2C Antibody

ProSci
Product Code: PSI-57-438
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-438-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Further Information

Additional Names:
Kinesin-like protein KIF2C, Kinesin-like protein 6, Mitotic centromere-associated kinesin, MCAK, KIF2C, KNSL6
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of kinesin-like protein family. Proteins of this family are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. This protein is important for anaphase chromosome segregation and may be required to coordinate the onset of sister centromere separation.
Background References:
  • Tanno, Y., et al. Genes Dev. 24(19):2169-2179(2010)
  • Gnjatic, S., et al. Int. J. Cancer 127(2):381-393(2010)
  • Sanhaji, M., et al. Mol. Cell. Biol. 30(11):2594-2607(2010)
  • Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This KIF2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-208 amino acids from the N-terminal region of human KIF2C.
NCBI Gene ID #:
11004
NCBI Official Name:
Kinesin-like protein KIF2C
NCBI Official Symbol:
KIF2C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
81 kDa
Protein Accession #:
Q99661
Protein GI Number:
20141607
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q99661
User NOte:
Optimal dilutions for each application to be determined by the researcher.