CDH16 Antibody
| Code | Size | Price |
|---|
| PSI-57-241-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the cadherin superfamily, genes
encoding calcium-dependent, membrane-associated glycoproteins.
Mapped to a previously identified cluster of cadherin genes on
chromosome 16q22.1, the gene localizes with superfamily members
CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an
extracellular domain containing 6 cadherin domains, a transmembrane
region and a truncated cytoplasmic domain but lacks the prosequence
and tripeptide HAV adhesion recognition sequence typical of most
classical cadherins. Expression is exclusively in kidney, where the
protein functions as the principal mediator of homotypic cellular
recognition, playing a role in the morphogenic direction of tissue
development.
Background References:
- Thedieck, C., et al. J. Mol. Biol. 378(1):145-153(2008)
- Kuehn, A., et al. Am. J. Surg. Pathol. 31(10):1528-1533(2007)
- Thedieck, C., et al. Br. J. Cancer 92(11):2010-2017(2005)
- Hishikawa, K., et al. Biochem. Biophys. Res. Commun. 328(1):288-291(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CDH16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 796-824 amino acids from the C-terminal region of human CDH16.
NCBI Gene ID #:
1014
NCBI Official Name:
Cadherin-16
NCBI Official Symbol:
CDH16
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
90 kDa
Protein Accession #:
O75309
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O75309
User NOte:
Optimal dilutions for each application to be determined by the researcher.