DUSP14 Antibody
| Code | Size | Price |
|---|
| PSI-60-909-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Dual specificity protein phosphatase 14, MKP-1-like protein tyrosine phosphatase, MKP-L, Mitogen-activated protein kinase phosphatase 6, MAP kinase phosphatase 6, MKP-6, DUSP14, MKP6
Application Note:
For WB starting dilution is: 1:1000
Background:
Dual-specificity phosphatases (DUSPs) constitute a large
heterogeneous subgroup of the type I cysteine-based
protein-tyrosine phosphatase superfamily. DUSPs are characterized
by their ability to dephosphorylate both tyrosine and
serine/threonine residues. They have been implicated as major
modulators of critical signaling pathways. DUSP14 contains the
consensus DUSP C-terminal catalytic domain but lacks the N-terminal
CH2 domain found in the MKP (mitogen-activated protein kinase
phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson
et al., 2009 [PubMed 19228121]).
Background References:
- Thye, T., et al. Nat. Genet. 42(9):739-741(2010)
- Lountos, G.T., et al. Acta Crystallogr.Biol. Crystallogr. 65 (PT 10), 1013-1020 (2009) :
- Patterson, K.I., et al. Biochem. J. 418(3):475-489(2009)
- Elass, E., et al. FEBS Lett. 582(3):445-450(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This DUSP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the Central region of human DUSP14.
NCBI Gene ID #:
11072
NCBI Official Name:
Dual specificity protein phosphatase 14
NCBI Official Symbol:
DUSP14
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
O95147
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O95147
User NOte:
Optimal dilutions for each application to be determined by the researcher.