HPS3 Antibody
Code | Size | Price |
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PSI-58-778-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Hermansky-Pudlak syndrome 3 protein, HPS3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein containing a potential
clathrin-binding motif, consensus dileucine signals, and
tyrosine-based sorting signals for targeting to vesicles of
lysosomal lineage. The encoded protein may play a role in organelle
biogenesis associated with melanosomes, platelet dense granules,
and lysosomes. Mutations in this gene are associated with
Hermansky-Pudlak syndrome type 3. Alternate splice variants exist,
but their full length sequence has not been determined. [provided
by RefSeq].
Background References:
- Torres-Serrant, M., et al. J. Pediatr. Hematol. Oncol. 32(6):448-453(2010)
- Huizing, M., et al. Platelets 18(2):150-157(2007)
- Santiago Borrero, P.J., et al. J. Invest. Dermatol. 126(1):85-90(2006)
- Boissy, R.E., et al. Am. J. Pathol. 166(1):231-240(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HPS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the N-terminal region of human HPS3.
NCBI Gene ID #:
84343
NCBI Official Name:
Hermansky-Pudlak syndrome 3 protein
NCBI Official Symbol:
HPS3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
114 kDa
Protein Accession #:
Q969F9
Protein GI Number:
20532121
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q969F9
User NOte:
Optimal dilutions for each application to be determined by the researcher.