GCNT2 Antibody
| Code | Size | Price |
|---|
| PSI-59-898-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A, N-acetylglucosaminyltransferase, I-branching enzyme, IGNT, GCNT2, GCNT5, II, NACGT1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the enzyme responsible for formation of
the blood group I antigen. The i and I antigens are distinguished
by linear and branched poly-N-acetyllactosaminoglycans,
respectively. The encoded protein is the I-branching enzyme, a
beta-1,6-N-acetylglucosaminyltransferase responsible for the
conversion of fetal i antigen to adult I antigen in erythrocytes
during embryonic development. Mutations in this gene have been
associated with adult i blood group phenotype. Alternatively
spliced transcript variants encoding different isoforms have been
described.
Background References:
- Twu, Y.C., et al. Blood 110(13):4526-4534(2007)
- Wang, L., et al. Biochem. Biophys. Res. Commun. 331(4):958-963(2005)
- Pras, E., et al. Invest. Ophthalmol. Vis. Sci. 45(6):1940-1945(2004)
- Inaba, N., et al. Blood 101(7):2870-2876(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GCNT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-240 amino acids from the Central region of human GCNT2.
NCBI Gene ID #:
2651
NCBI Official Name:
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A
NCBI Official Symbol:
GCNT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
Q8N0V5
Protein GI Number:
298351849
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8N0V5
User NOte:
Optimal dilutions for each application to be determined by the researcher.