PTCRA Antibody

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ProSci
Product Code: PSI-60-241
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-60-241-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).
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Western blot analysis in K562 cell line lysates (35ug/lane).

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Further Information

Additional Names:
Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA
Application Note:
For WB starting dilution is: 1:1000
Background:
In immature T cells the T-cell receptor beta-chain gene (TCRB; MIM 186930) is rearranged and expressed before the TCRA (MIM 186880) chain. At this early stage, TCRB can associate with the pre-T-cell receptor alpha chain (PTCRA). The PTCRA, together with TCRB and the CD3 complex (see MIM 186740), minimally make up the pre-T cell receptor (pre-TCR), which regulates early T cell development.
Background References:
  • Velez, D.R., et al. Am. J. Obstet. Gynecol. 200 (2), 209 (2009) :
  • Menon, R., et al. Reprod. Biol. Endocrinol. 7, 62 (2009) :
  • Velez, D.R., et al. PLoS ONE(9), E3283 (2008) :
  • Navarro, M.N., et al. Blood 110(13):4331-4340(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PTCRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the C-terminal region of human PTCRA.
NCBI Gene ID #:
171558
NCBI Official Name:
Pre T-cell antigen receptor alpha
NCBI Official Symbol:
PTCRA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
Q6ISU1
Protein GI Number:
74736631
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q6ISU1
User NOte:
Optimal dilutions for each application to be determined by the researcher.