SNX15 Antibody
| Code | Size | Price |
|---|
| PSI-58-666-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Sorting nexin-15, SNX15
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the sorting nexin family.
Members of this family contain a phox (PX) domain, which is a
phosphoinositide binding domain, and are involved in intracellular
trafficking. Overexpression of this gene results in a decrease in
the processing of insulin and hepatocyte growth factor receptors to
their mature subunits. This decrease is caused by the
mislocalization of furin, the endoprotease responsible for cleavage
of insulin and hepatocyte growth factor receptors. This protein is
involved in endosomal trafficking from the plasma membrane to
recycling endosomes or the trans-Golgi network. This gene encodes
two transcript variants encoding distinct isoforms. [provided by
RefSeq].
Background References:
- Venter, J.C., et al. Science 291(5507):1304-1351(2001)
- Phillips, S.A., et al. J. Biol. Chem. 276(7):5074-5084(2001)
- Barr, V.A., et al. Traffic 1(11):904-916(2000)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SNX15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-251 amino acids from the C-terminal region of human SNX15.
NCBI Gene ID #:
29907
NCBI Official Name:
Sorting nexin-15
NCBI Official Symbol:
SNX15
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
Protein Accession #:
Q9NRS6
Protein GI Number:
13124562
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9NRS6
User NOte:
Optimal dilutions for each application to be determined by the researcher.