EPB49 Antibody
| Code | Size | Price |
|---|
| PSI-58-591-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Dematin, Dematin actin-binding protein, Erythrocyte membrane protein band 49, DMTN, DMT, EPB49
Application Note:
For WB starting dilution is: 1:1000
Background:
Dematin, or EPB49, is an actin-bundling protein originally
identified in the erythroid membrane skeleton. Its actin-bundling
activity is abolished upon phosphorylation by cAMP-dependent
protein kinase and is restored after dephosphorylation (Rana et
al., 1993 [PubMed 8341682]).
Background References:
- Vugmeyster, L., et al. J. Biomol. NMR 47(2):155-162(2010)
- Chen, L., et al. Protein Sci. 18(3):629-636(2009)
- Vugmeyster, L., et al. J. Biomol. NMR 43(1):39-50(2009)
- Vermeulen, W., et al. J. Mol. Biol. 359(5):1277-1292(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This EPB49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 amino acids from the Central region of human EPB49.
NCBI Gene ID #:
2039
NCBI Official Name:
Dematin
NCBI Official Symbol:
DMTN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
Q08495
Protein GI Number:
22654240
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q08495
User NOte:
Optimal dilutions for each application to be determined by the researcher.