ZFYVE1 Antibody

ProSci
Product Code: PSI-56-439
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-439-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in human placenta tissue lysates (35ug/lane).

Western blot analysis in human placenta tissue lysates (35ug/lane).

Further Information

Additional Names:
Zinc finger FYVE domain-containing protein 1, Double FYVE-containing protein 1, SR3, Tandem FYVE fingers-1, ZFYVE1, DFCP1, KIAA1589, TAFF1, ZNFN2A1
Application Note:
For WB starting dilution is: 1:1000
Background:
The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. This gene encodes a protein which contains two zinc-binding FYVE domains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes.
Background References:
  • Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)
  • Heilig, R., et al. Nature 421(6923):601-607(2003)
  • Krugmann, S., et al. Mol. Cell 9(1):95-108(2002)
  • Ridley, S.H., et al. J. Cell. Sci. 114 (PT 22), 3991-4000 (2001) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ZFYVE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-173 amino acids from the N-terminal region of human ZFYVE1.
NCBI Gene ID #:
53349
NCBI Official Name:
Zinc finger FYVE domain-containing protein 1
NCBI Official Symbol:
ZFYVE1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
87 kDa
Protein Accession #:
Q9HBF4
Protein GI Number:
34098716
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9HBF4
User NOte:
Optimal dilutions for each application to be determined by the researcher.