CHMP5 Antibody
| Code | Size | Price |
|---|
| PSI-59-959-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Charged multivesicular body protein 5, Chromatin-modifying protein 5, SNF7 domain-containing protein 2, Vacuolar protein sorting-associated protein 60, Vps60, hVps60, CHMP5, C9orf83, SNF7DC2
Application Note:
For WB starting dilution is: 1:1000
Background:
CHMP5 belongs to the chromatin-modifying protein/charged
multivesicular body protein (CHMP) family. These proteins are
components of ESCRT-III (endosomal sorting complex required for
transport III), a complex involved in degradation of surface
receptor proteins and formation of endocytic multivesicular bodies
(MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular
distributions, and one such CHMP, CHMP1A (MIM 164010), is required
for both MVB formation and regulation of cell cycle progression
(Tsang et al., 2006 [PubMed 16730941]).
Background References:
- Wang, H.R., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 16(2):282-285(2008)
- Row, P.E., et al. J. Biol. Chem. 282(42):30929-30937(2007)
- Huang, H.H., et al. Zhongguo Shi Yan Xue Ye Xue Za Zhi 15(4):738-742(2007)
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This CHMP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-204 amino acids from the C-terminal region of human CHMP5.
NCBI Gene ID #:
51510
NCBI Official Name:
Charged multivesicular body protein 5
NCBI Official Symbol:
CHMP5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
Q9NZZ3
Protein GI Number:
51702157
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9NZZ3
User NOte:
Optimal dilutions for each application to be determined by the researcher.