RGS11 Antibody
| Code | Size | Price |
|---|
| PSI-58-884-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Regulator of G-protein signaling 11, RGS11, RGS11
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene belongs to the RGS
(regulator of G protein signaling) family. Members of the RGS
family act as GTPase-activating proteins on the alpha subunits of
heterotrimeric, signal-transducing G proteins. This protein
inhibits signal transduction by increasing the GTPase activity of G
protein alpha subunits, thereby driving them into their inactive
GDP-bound form. Alternative splicing occurs at this locus and two
transcript variants encoding distinct isoforms have been
identified.
Background References:
- Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)
- Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
- Saleem, Y., et al. Biochem. Biophys. Res. Commun. 386(1):65-70(2009)
- Martin, J., et al. Nature 432(7020):988-994(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RGS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human RGS11.
NCBI Gene ID #:
8786
NCBI Official Name:
Regulator of G-protein signaling 11
NCBI Official Symbol:
RGS11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
O94810
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O94810
User NOte:
Optimal dilutions for each application to be determined by the researcher.