RGS13 Antibody
| Code | Size | Price |
|---|
| PSI-60-549-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Regulator of G-protein signaling 13, RGS13, RGS13
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the
regulator of G protein signaling (RGS) family. RGS family members
share similarity with S. cerevisiae SST2 and C. elegans egl-10
proteins, which contain a characteristic conserved RGS domain. RGS
proteins accelerate GTPase activity of G protein alpha-subunits,
thereby driving G protein into their inactive GDP-bound form, thus
negatively regulating G protein signaling. RGS proteins have been
implicated in the fine tuning of a variety of cellular events in
response to G protein-coupled receptor activation. The biological
function of this gene, however, is unknown. Two transcript variants
encoding the same isoform exist.
Background References:
- Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)
- Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
- Bansal, G., et al. J. Immunol. 181(11):7882-7890(2008)
- Han, J.I., et al. J. Leukoc. Biol. 79(6):1357-1368(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RGS13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the Central region of human RGS13.
NCBI Gene ID #:
6003
NCBI Official Name:
Regulator of G-protein signaling 13
NCBI Official Symbol:
RGS13
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
19 kDa
Protein Accession #:
O14921
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O14921
User NOte:
Optimal dilutions for each application to be determined by the researcher.