NFKBIL2 Antibody
| Code | Size | Price |
|---|
| PSI-59-419-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tonsoku-like protein, Inhibitor of kappa B-related protein, I-kappa-B-related protein, IkappaBR, NF-kappa-B inhibitor-like protein 2, Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2, TONSL, IKBR, NFKBIL2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is thought to be a
negative regulator of NF-kappa-B mediated transcription. The
encoded protein may bind NF-kappa-B complexes and trap them in the
cytoplasm, preventing them from entering the nucleus and
interacting with the DNA. Phosphorylation of this protein targets
it for degradation by the ubiquitination pathway, which frees the
NF-kappa-B complexes to enter the nucleus.
Background References:
- Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010)
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
- Norman, D.A., et al. Ann. Hum. Genet. 64 (PT 1), 15-23 (2000) :
- Ray, P., et al. J. Biol. Chem. 270(18):10680-10685(1995)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NFKBIL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 amino acids from the N-terminal region of human NFKBIL2.
NCBI Gene ID #:
4796
NCBI Official Name:
Tonsoku-like protein
NCBI Official Symbol:
TONSL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
151 kDa
Protein Accession #:
Q96HA7
Protein GI Number:
182662416
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q96HA7
User NOte:
Optimal dilutions for each application to be determined by the researcher.