TIAM1 Antibody
| Code | Size | Price |
|---|
| PSI-60-795-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
T-lymphoma invasion and metastasis-inducing protein 1, TIAM-1, TIAM1
Application Note:
For WB starting dilution is: 1:1000
Background:
Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.
Background References:
- Yang, W., et al. Jpn. J. Clin. Oncol. 40(11):1053-1059(2010)
- Moriarty, C.H., et al. J. Biol. Chem. 285(27):20541-20546(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Rajagopal, S., et al. J. Biol. Chem. 285(23):18060-18071(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This TIAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1478-1506 amino acids from the C-terminal region of human TIAM1.
NCBI Gene ID #:
7074
NCBI Official Name:
T-lymphoma invasion and metastasis-inducing protein 1
NCBI Official Symbol:
TIAM1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
178 kDa
Protein Accession #:
Q13009
Protein GI Number:
152031709
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q13009
User NOte:
Optimal dilutions for each application to be determined by the researcher.