PEX12 Antibody
| Code | Size | Price |
|---|
| PSI-64-021-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Peroxisome assembly protein 12, Peroxin-12, Peroxisome assembly factor 3, PAF-3, PEX12, PAF3
Application Note:
For WB starting dilution is: 1:1000
Background:
Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle.
Background References:
- Zeharia, A., et al. J. Hum. Genet. 52(7):599-606(2007)
- Mano, S., et al. Plant J. 47(4):604-618(2006)
- Gootjes, J., et al. Hum. Mutat. 24(2):130-139(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This PEX12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-158 amino acids from the Central region of human PEX12.
NCBI Gene ID #:
5193
NCBI Official Name:
Peroxisome assembly protein 12
NCBI Official Symbol:
PEX12
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
O00623
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O00623
User NOte:
Optimal dilutions for each application to be determined by the researcher.