TTPA Antibody
| Code | Size | Price |
|---|
| PSI-60-826-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Alpha-tocopherol transfer protein, Alpha-TTP, TTPA, TPP1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a soluble protein that binds
alpha-trocopherol, a form of vitamin E, with high selectivity and
affinity. This protein plays an important role in regulating
vitamin E levels in the body by transporting vitamin E between
membrane vesicles and facilitating the secretion of vitamin E from
hepatocytes to circulating lipoproteins. Mutations in this gene
cause hereditary vitamin E deficiency (ataxia with vitamin E
deficiency, AVED) and retinitis pigmentosa.
Background References:
- Zhang, W.X., et al. Lipids 44(7):631-641(2009)
- Wright, M.E., et al. Cancer Res. 69(4):1429-1438(2009)
- Fusco, C., et al. J. Child Neurol. 23(11):1328-1330(2008)
- Rotzoll, D.E., et al. Eur. J. Obstet. Gynecol. Reprod. Biol. 140(2):183-191(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This TTPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-108 amino acids from the Central region of human TTPA.
NCBI Gene ID #:
7274
NCBI Official Name:
Alpha-tocopherol transfer protein
NCBI Official Symbol:
TTPA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
P49638
Protein GI Number:
1351322
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P49638
User NOte:
Optimal dilutions for each application to be determined by the researcher.