FRS2 Antibody

ProSci
Product Code: PSI-60-155
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-155-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution Lane 1: MCF-7 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:1000 dilution Lane 1: MCF-7 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Fibroblast growth factor receptor substrate 2, FGFR substrate 2, FGFR-signaling adaptor SNT, Suc1-associated neurotrophic factor target 1, SNT-1, FRS2
Application Note:
For WB starting dilution is: 1:1000
Background:
Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Background References:
  • Zhou, W., et al. Cell Res. 19(10):1165-1177(2009)
  • Cha, J.Y., et al. J. Biol. Chem. 284(10):6227-6240(2009)
  • Li, M., et al. J. Dermatol. Sci. 53(3):182-191(2009)
  • Turner, S.T., et al. Hypertension 52(2):359-365(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FRS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-303 amino acids from the Central region of human FRS2.
NCBI Gene ID #:
10818
NCBI Official Name:
Fibroblast growth factor receptor substrate 2
NCBI Official Symbol:
FRS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
Q8WU20
Protein GI Number:
209572769
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8WU20
User NOte:
Optimal dilutions for each application to be determined by the researcher.