MTMR6 Antibody

ProSci
Product Code: PSI-58-558
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-558-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in HL-60 cell line lysates (35ug/lane).

Western blot analysis in HL-60 cell line lysates (35ug/lane).

Further Information

Additional Names:
Myotubularin-related protein 6, 313-, MTMR6
Application Note:
For WB starting dilution is: 1:1000
Background:
Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells.
Background References:
  • Zou, J., et al. J. Biol. Chem. 284(4):2064-2071(2009)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
  • Srivastava, S., et al. Mol. Cell. Biol. 26(15):5595-5602(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MTMR6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of human MTMR6.
NCBI Gene ID #:
9107
NCBI Official Name:
Myotubularin-related protein 6
NCBI Official Symbol:
MTMR6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
72 kDa
Protein Accession #:
Q9Y217
Protein GI Number:
317373414
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q9Y217
User NOte:
Optimal dilutions for each application to be determined by the researcher.