NUP43 Antibody

ProSci
Product Code: PSI-59-121
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-121-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Jurkat cell line lysates (35ug/lane).

Western blot analysis in Jurkat cell line lysates (35ug/lane).

Further Information

Additional Names:
Nucleoporin Nup43, Nup107-160 subcomplex subunit Nup43, p42, NUP43
Application Note:
For WB starting dilution is: 1:1000
Background:
Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).
Background References:
  • Zuccolo, M., et al. EMBO J. 26(7):1853-1864(2007)
  • Glavy, J.S., et al. Proc. Natl. Acad. Sci. U.S.A. 104(10):3811-3816(2007)
  • Loiodice, I., et al. Mol. Biol. Cell 15(7):3333-3344(2004)
  • Le Rouzic, E., et al. J. Biol. Chem. 277(47):45091-45098(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NUP43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-171 amino acids from the Central region of human NUP43.
NCBI Gene ID #:
348995
NCBI Official Name:
Nucleoporin Nup43
NCBI Official Symbol:
NUP43
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
Q8NFH3
Protein GI Number:
27923819
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8NFH3
User NOte:
Optimal dilutions for each application to be determined by the researcher.