PSTPIP1 Antibody
| Code | Size | Price |
|---|
| PSI-56-465-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Proline-serine-threonine phosphatase-interacting protein 1, PEST phosphatase-interacting protein 1, CD2-binding protein 1, H-PIP, PSTPIP1, CD2BP1
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
The protein encoded by this gene binds to the cytoplasmic
tail of CD2, an effector of T cell activation and adhesion,
negatively affecting CD2-triggered T cell activation. The encoded
protein appears to be a scaffold protein and a regulator of the
actin cytoskeleton. It has also been shown to bind ABL1, PTPN18,
WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA
syndrome.
Background References:
- Andre, M.F., et al. Dig. Dis. Sci. 55(6):1681-1688(2010)
- Rose, J. Phd, et al. Mol. Med. (2010) In press :
- Hong, J.B., et al. J. Am. Acad. Dermatol. 61(3):533-535(2009)
- Voss, M., et al. BMC Immunol. 10, 53 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PSTPIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the N-terminal region of human PSTPIP1.
NCBI Gene ID #:
9051
NCBI Official Name:
Proline-serine-threonine phosphatase-interacting protein 1
NCBI Official Symbol:
PSTPIP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
O43586
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
O43586
User NOte:
Optimal dilutions for each application to be determined by the researcher.