MAML1 Antibody
| Code | Size | Price |
|---|
| PSI-55-913-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Mastermind-like protein 1, Mam-1, MAML1 (HGNC:13632)
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This protein is the human homolog of mastermind, a
Drosophila protein that plays a role in the Notch signaling pathway
involved in cell-fate determination. There is in vitro evidence
that the human homolog forms a complex with the intracellular
portion of human Notch receptors and can increase expression of a
Notch-induced gene. This evidence supports its proposed function as
a transcriptional co-activator in the Notch signaling pathway.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Lindberg, M.J., et al. FASEB J. 24(7):2396-2404(2010)
- Hao, L., et al. Oncogene 29(2):201-213(2010)
- Saint Just Ribeiro, M., et al. Curr. Protein Pept. Sci. 10(6):570-576(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MAML1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-225 amino acids from the Central region of human MAML1.
NCBI Gene ID #:
9794
NCBI Official Name:
Mastermind-like protein 1
NCBI Official Symbol:
MAML1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
108 kDa
Protein Accession #:
Q92585
Protein GI Number:
68565602
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q92585
User NOte:
Optimal dilutions for each application to be determined by the researcher.