SNIP1 Antibody

ProSci
Product Code: PSI-56-302
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-302-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Jurkat cell line lysates (35ug/lane).
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Flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Western blot analysis in Jurkat cell line lysates (35ug/lane).
Flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Further Information

Additional Names:
Smad nuclear-interacting protein 1, FHA domain-containing protein SNIP1, SNIP1
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. SNIP1 is involved in the microRNA (miRNA) biogenesis.
Background References:
  • Bracken, C.P., et al. Cancer Res. 68(18):7621-7628(2008)
  • Yu, B., et al. Proc. Natl. Acad. Sci. U.S.A. 105(29):10073-10078(2008)
  • Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
  • Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This SNIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-118 amino acids from the N-terminal region of human SNIP1.
NCBI Gene ID #:
79753
NCBI Official Name:
Smad nuclear-interacting protein 1
NCBI Official Symbol:
SNIP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
Q8TAD8
Protein GI Number:
48428655
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
Q8TAD8
User NOte:
Optimal dilutions for each application to be determined by the researcher.