TPM4 Antibody
| Code | Size | Price |
|---|
| PSI-56-627-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Tropomyosin alpha-4 chain, TM30p1, Tropomyosin-4, TPM4
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene encodes a member of the tropomyosin family of
actin-binding proteins involved in the contractile system of
striated and smooth muscles and the cytoskeleton of non-muscle
cells. Tropomyosins are dimers of coiled-coil proteins that
polymerize end-to-end along the major groove in most actin
filaments. They provide stability to the filaments and regulate
access of other actin-binding proteins. In muscle cells, they
regulate muscle contraction by controlling the binding of myosin
heads to the actin filament. Multiple transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].
Background References:
- Martins-de-Souza, D., et al.Psychiatr Res 44(14):989-991(2010)
- Vlahovich, N., et al. Cell Motil. Cytoskeleton 65(1):73-85(2008)
- Montesano Gesualdi, N., et al. Free Radic. Res. 40(5):467-476(2006)
- Hossain, M.M., et al. J. Biol. Chem. 280(51):42442-42453(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Pig
Immunogen:
This TPM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human TPM4.
NCBI Gene ID #:
7171
NCBI Official Name:
Tropomyosin alpha-4 chain
NCBI Official Symbol:
TPM4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
P67936
Protein GI Number:
54039751
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P67936
User NOte:
Optimal dilutions for each application to be determined by the researcher.