TCF4 Antibody
Code | Size | Price |
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PSI-62-039-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Transcription factor 4, TCF-4, Class B basic helix-loop-helix protein 19, bHLHb19, Immunoglobulin transcription factor 2, ITF-2, SL3-3 enhancer factor 2, SEF-2, TCF4, BHLHB19, ITF2, SEF2
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
TCF4 is transcription factor 4, a basic
helix-turn-helix transcription factor. The encoded protein
recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a
motif first identified in immunoglobulin enhancers. This gene is
expressed predominantly in pre-B-cells, although it is found in
other tissues as well. Defects in this gene are a cause of
Pitt-Hopkins syndrome.
Background References:
- Rosenfeld, J.A., et al. Genet. Med. 11(11):797-805(2009)
- Herbst, A., et al. Biochem. Biophys. Res. Commun. 387(4):736-740(2009)
- Rena, V., et al. Placenta 30(10):876-883(2009)
- Henthorn, P., et al. Science 247(4941):467-470(1990)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This TCF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-73 amino acids from the N-terminal region of human TCF4.
NCBI Gene ID #:
6925
NCBI Official Name:
Transcription factor 4
NCBI Official Symbol:
TCF4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
71 kDa
Protein Accession #:
P15884
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P15884
User NOte:
Optimal dilutions for each application to be determined by the researcher.