TRIM23 Antibody
| Code | Size | Price |
|---|
| PSI-57-172-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
E3 ubiquitin-protein ligase TRIM23, 632-, ADP-ribosylation factor domain-containing protein 1, GTP-binding protein ARD-1, RING finger protein 46, Tripartite motif-containing protein 23, TRIM23, ARD1, ARFD1, RNF46
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a member of the
tripartite motif (TRIM) family. The TRIM motif includes three
zinc-binding domains, a RING, a B-box type 1 and a B-box type 2,
and a coiled-coil region. This protein is also a member of the ADP
ribosylation factor family of guanine nucleotide-binding family of
proteins. Its carboxy terminus contains an ADP-ribosylation factor
domain and a guanine nucleotide binding site, while the amino
terminus contains a GTPase activating protein domain which acts on
the guanine nucleotide binding site. The protein localizes to
lysosomes and the Golgi apparatus. It plays a role in the formation
of intracellular transport vesicles, their movement from one
compartment to another, and phopholipase D activation. Three
alternatively spliced transcript variants for this gene have been
described.
Background References:
- Arimoto, K., et al. Proc. Natl. Acad. Sci. U.S.A. 107(36):15856-15861(2010)
- Poole, E., et al. J. Virol. 83(8):3581-3590(2009)
- Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
- Vichi, A., et al. Proc. Natl. Acad. Sci. U.S.A. 102(6):1945-1950(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This TRIM23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the N-terminal region of human TRIM23.
NCBI Gene ID #:
373
NCBI Official Name:
E3 ubiquitin-protein ligase TRIM23
NCBI Official Symbol:
TRIM23
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
64 kDa
Protein Accession #:
P36406
Protein GI Number:
543839
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Signal Transduction
Swissprot #:
P36406
User NOte:
Optimal dilutions for each application to be determined by the researcher.